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Ionis Pharmaceuticals

46.75

+1.914.26%

Post-market: 46.50-0.2500-0.53%19:30 EDT

Volume:4.08M

Turnover:190.12M

Market Cap:7.77B

PE:-13.43

High:47.42

Open:46.68

Low:45.75

Close:44.84

52wk High:86.74

52wk Low:44.66

Shares:166.18M

Float Shares:161.92M

Volume Ratio:0.79

T/O Rate:2.52%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:17.67

PE(LYR):-19.63

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Overview Company News Filings

Ionis Pharmaceuticals Adds Veteran Leader to Board

Ionis adds former Alexion CEO Ludwig Hantson to board

BRIEF-Ionis Announces Appointment Of Ludwig Hantson, Ph.D. To Board Of Directors

Ionis Announces Appointment of Ludwig Hantson, Ph.d. to Board of Directors

THOMSON REUTERS

Ionis Pharmaceuticals (IONS) Receives a Buy from Guggenheim

Ionis posts presentation for 2026 annual shareholders meeting

Ionis director Spencer R. Berthelsen disposes of 8,000 common shares for $605,360

Ionis Pharmaceuticals Price Target Maintained With a $125.00/Share by HC Wainwright & Co.

Ionis Pharmaceuticals: Advancing Pipeline, HBV Phase III Success, and Robust Catalyst Flow Underpin Buy Rating

Ionis partner GSK reports B-Well 1, B-Well 2 trials meet primary endpoint

Ionis Partner GSK Announces Bepirovirsen Achieves Unprecedented Functional Cure Rates With Potential to Redefine Treatment for Chronic Hepatitis B

THOMSON REUTERS

A New, Powerful Cholesterol-Lowering Drug Is on the Horizon -- WSJ

U.S. RESEARCH ROUNDUP-CAVA Group, Eagle Materials, Vertiv

J.P. Morgan Sticks to Their Buy Rating for Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals Initiated at Buy by Citigroup

Ionis Pharmaceuticals initiated with a Buy, named a top pick at Citi

Assessing Ionis Pharmaceuticals (IONS) Valuation As Shares Cool After A Multi Year Run

Simply Wall St.

Ionis CEO Brett P. Monia disposes of USD 361,478 common shares

Ionis Pharmaceuticals participates in a conference call with Cantor

BRIEF-Ionis Partner Biogen Announces Topline Results From Phase 2 Celia Study Of Diranersen

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Pharmaceuticals Adds Veteran Leader to Board","url":"https://stock-news.laohu8.com/highlight/detail?id=2642139435","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642139435?lang=en_us&edition=fundamental","pubTime":"2026-06-09 01:19","pubTimestamp":1780939199,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals ( ($IONS) ) just unveiled an update. Ionis Pharmaceuticals on June 4, 2026, appointed veteran biopharmaceutical executive Lud...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/ionis-pharmaceuticals-adds-veteran-leader-to-board?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/ionis-pharmaceuticals-adds-veteran-leader-to-board?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2642803435","title":"Ionis adds former Alexion CEO Ludwig Hantson to board","url":"https://stock-news.laohu8.com/highlight/detail?id=2642803435","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642803435?lang=en_us&edition=fundamental","pubTime":"2026-06-09 00:50","pubTimestamp":1780937418,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals named former Alexion CEO Ludwig Hantson to its board, effective immediately.Hantson led Alexion from 2017 to 2021 through its sale to AstraZeneca.He previously ran Baxter Bioscience, led the Baxalta spin-off as CEO, held senior roles at Novartis, spent 13 years at Johnson & Johnson.Ionis also added Peter Reikes to the board.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 08, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260608:nNDL7bKzYL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE000M9KFDE8.USD","LU2023250330.USD","LU1829250122.USD","LU0795875086.SGD","LU0889566641.SGD","JNJ","LU0949170772.SGD","LU2433249047.HKD","LU2237443978.SGD","LU1119994496.HKD","LU2456880835.USD","IE0000B7K699.USD","LU0887340254.USD","IONS","LU2023251221.USD","LU1481599808.USD","LU2236285917.USD","IE0002141913.USD","LU1732800096.USD","IE00B19Z3B42.SGD","LU0823416689.USD","IE00BVYPNV92.GBP","LU1023059063.AUD","IE00BZ1G4Q59.USD","LU0912757837.SGD","LU1551013425.SGD","BK4581","LU0957799991.USD","LU0070217475.USD","LU1989772840.SGD","03165","LU1496350171.SGD","LU2114397693.USD","LU2237443549.SGD","IE00B7SZLL34.SGD","LU2357627491.SGD","LU2293690082.USD","IE0034235188.USD","BK4550","LU0976567544.SGD","LU1051770623.HKD","LU1162221912.USD","LU2896262040.SGD","LU1880407132.USD","LU1894683348.USD","LU0158827948.USD","LU0128525689.USD","LU2129689431.USD","LU2592432038.USD","AZN.UK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641648678","title":"BRIEF-Ionis Announces Appointment Of Ludwig Hantson, Ph.D. To Board Of Directors","url":"https://stock-news.laohu8.com/highlight/detail?id=2641648678","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641648678?lang=en_us&edition=fundamental","pubTime":"2026-06-08 19:09","pubTimestamp":1780916962,"startTime":"0","endTime":"0","summary":"BRIEF-Ionis Announces Appointment Of Ludwig Hantson, Ph.D. To Board Of DirectorsJune 8 (Reuters) - Ionis Pharmaceuticals Inc IONS.O:IONIS ANNOUNCES APPOINTMENT OF LUDWIG HANTSON, PH.D. TO BOARD OF DIR","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260608:nTUA9G63LF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641869554","title":"Ionis Announces Appointment of Ludwig Hantson, Ph.d. to Board of Directors","url":"https://stock-news.laohu8.com/highlight/detail?id=2641869554","media":"THOMSON REUTERS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641869554?lang=en_us&edition=fundamental","pubTime":"2026-06-08 19:00","pubTimestamp":1780916401,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260608:nTUA9G63LF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641144535","title":"Ionis Pharmaceuticals (IONS) Receives a Buy from Guggenheim","url":"https://stock-news.laohu8.com/highlight/detail?id=2641144535","media":"TIPRANKS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641144535?lang=en_us&edition=fundamental","pubTime":"2026-06-06 01:05","pubTimestamp":1780679114,"startTime":"0","endTime":"0","summary":"In a report released today, from Guggenheim maintained a Buy rating on Ionis Pharmaceuticals, with a price target of $106.00. The word on The Stree...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-buy-from-guggenheim-blurbs-news-2?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ionis-pharmaceuticals-ions-receives-a-buy-from-guggenheim-blurbs-news-2?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641160372","title":"Ionis posts presentation for 2026 annual shareholders meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2641160372","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641160372?lang=en_us&edition=fundamental","pubTime":"2026-06-05 05:29","pubTimestamp":1780608587,"startTime":"0","endTime":"0","summary":"Ionis shareholder meeting deck outlined a push to accelerate revenue growth toward sustained positive cash flow, targeting cash flow breakeven in 2028.DAWNZERA U.S. net product sales reached $16 million in Q1 2026, up 128% from Q4 2025.TRYNGOLZA U.S. net product sales totaled $27 million in Q1 2026, up 350% from Q1 2025; EU launch underway.Zilganersen for Alexander disease received FDA priority review with a PDUFA date of Sept. 22, 2026; positioned as the first independent neurology launch expected in 2026.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief on June 04, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260604:nNDL3QjmmX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640182914","title":"Ionis director Spencer R. Berthelsen disposes of 8,000 common shares for $605,360","url":"https://stock-news.laohu8.com/highlight/detail?id=2640182914","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640182914?lang=en_us&edition=fundamental","pubTime":"2026-06-04 05:35","pubTimestamp":1780522507,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals director Spencer R. Berthelsen exercised options to buy 8,000 shares at USD 24.42 on June 1.He sold 8,000 shares at USD 75.67 the same day.He reported 156,013 shares owned directly following the transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 03, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260603:nNDLcqJ57:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis director Spencer R. Berthelsen disposes of 8,000 common shares for $605,360","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640995931","title":"Ionis Pharmaceuticals Price Target Maintained With a $125.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2640995931","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640995931?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:45","pubTimestamp":1780314300,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  June 01, 2026 07:45 ET (11:45 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639692011","title":"Ionis Pharmaceuticals: Advancing Pipeline, HBV Phase III Success, and Robust Catalyst Flow Underpin Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2639692011","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639692011?lang=en_us&edition=fundamental","pubTime":"2026-05-28 23:45","pubTimestamp":1779983121,"startTime":"0","endTime":"0","summary":"William Blair analyst Myles Minter has reiterated their bullish stance on IONS stock, giving a Buy rating today. Myles Minter has given his Buy rat...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-advancing-pipeline-hbv-phase-iii-success-and-robust-catalyst-flow-underpin-buy-rating-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/ionis-pharmaceuticals-advancing-pipeline-hbv-phase-iii-success-and-robust-catalyst-flow-underpin-buy-rating-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["III","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638696556","title":"Ionis partner GSK reports B-Well 1, B-Well 2 trials meet primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2638696556","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638696556?lang=en_us&edition=fundamental","pubTime":"2026-05-28 17:21","pubTimestamp":1779960078,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) partner GSK (GSK) announced data for bepirovirsen, an investigational antisense oligonucleotide for the treatment of c...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-partner-gsk-reports-b-well-1-b-well-2-trials-meet-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-partner-gsk-reports-b-well-1-b-well-2-trials-meet-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4585","GSKH","BK4588","GSK.UK","LU1829250122.USD","BK4007","IONS","BK4139","BK4532","GSK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638666828","title":"Ionis Partner GSK Announces Bepirovirsen Achieves Unprecedented Functional Cure Rates With Potential to Redefine Treatment for Chronic Hepatitis B","url":"https://stock-news.laohu8.com/highlight/detail?id=2638666828","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638666828?lang=en_us&edition=fundamental","pubTime":"2026-05-28 16:45","pubTimestamp":1779957902,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260528:nTUA1MND9V:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638684413","title":"A New, Powerful Cholesterol-Lowering Drug Is on the Horizon -- WSJ","url":"https://stock-news.laohu8.com/highlight/detail?id=2638684413","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638684413?lang=en_us&edition=fundamental","pubTime":"2026-05-28 00:00","pubTimestamp":1779897600,"startTime":"0","endTime":"0","summary":"A new class of drugs is poised to take on an insidious cause of heart attacks and strokes that has eluded treatment for decades.Amgen and Eli Lilly are also developing medicines that lower the level of lipoprotein, a fatty particle in the blood that is known as Lp. It can cause plaque to build up in blood vessels and is linked to heart disease.Tens of millions of people in the U.S. have elevated Lp, an inherited and largely hidden driver of heart disease. If Lp drugs work, companies could be on the verge of the next big heart-drug market. Citi analysts estimate it could be valued at as much as $25 billion a year worldwide.This isn't a sure bet, though. Effective Lp drugs have proven difficult to develop. In the past, scientists found drugs that lowered levels of the particle a moderate amount but failed to reduce heart attacks and strokes in research studies, leaving patients with no approved 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Morgan Sticks to Their Buy Rating for Ionis Pharmaceuticals (IONS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2636657948","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636657948?lang=en_us&edition=fundamental","pubTime":"2026-05-20 01:55","pubTimestamp":1779213325,"startTime":"0","endTime":"0","summary":"In a report released today, Eric Joseph from J.P. Morgan maintained a Buy rating on Ionis Pharmaceuticals, with a price target of $115.00. Accordin...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/j-p-morgan-sticks-to-their-buy-rating-for-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/j-p-morgan-sticks-to-their-buy-rating-for-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636857341","title":"Ionis Pharmaceuticals Initiated at Buy by Citigroup","url":"https://stock-news.laohu8.com/highlight/detail?id=2636857341","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636857341?lang=en_us&edition=fundamental","pubTime":"2026-05-19 22:37","pubTimestamp":1779201420,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  May 19, 2026 10:37 ET (14:37 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636009293","title":"Ionis Pharmaceuticals initiated with a Buy, named a top pick at Citi","url":"https://stock-news.laohu8.com/highlight/detail?id=2636009293","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636009293?lang=en_us&edition=fundamental","pubTime":"2026-05-19 04:21","pubTimestamp":1779135661,"startTime":"0","endTime":"0","summary":"Citi initiated coverage of Ionis Pharmaceuticals (IONS) with a Buy rating and $115 price target and named it a top pick among small-to-mid cap biot...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-initiated-with-a-buy-named-a-top-pick-at-citi-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-initiated-with-a-buy-named-a-top-pick-at-citi-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635506673","title":"Assessing Ionis Pharmaceuticals (IONS) Valuation As Shares Cool After A Multi Year Run","url":"https://stock-news.laohu8.com/highlight/detail?id=2635506673","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635506673?lang=en_us&edition=fundamental","pubTime":"2026-05-16 23:33","pubTimestamp":1778945608,"startTime":"0","endTime":"0","summary":"Recent stock performance and context\nIonis Pharmaceuticals (IONS) has seen its stock give back some ground recently, with the price down about 2% over the past week and roughly 1% over the past month, against a 7% decline over the past 3 months.\nSee our latest analysis for Ionis Pharmaceuticals.\nZooming out, Ionis Pharmaceuticals’ share price has cooled recently. However, its 1-year total shareholder return of 121.19% and 3-year total shareholder return of 89.41% indicate that longer term...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/assessing-ionis-pharmaceuticals-ions-valuation-as-shares-coo","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/assessing-ionis-pharmaceuticals-ions-valuation-as-shares-coo","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635558360","title":"Ionis CEO Brett P. Monia disposes of USD 361,478 common shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2635558360","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635558360?lang=en_us&edition=fundamental","pubTime":"2026-05-16 06:15","pubTimestamp":1778883355,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals CEO and director Brett P. Monia sold 4,536 shares of common stock in transactions dated May 13-14.Sales were executed at weighted average prices of $78.01 and $78.68.Monia acquired 4,536 shares via option exercises at $32.6 per share.Directly held common stock position stood at 242,662 shares after the transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 15, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260515:nNDL15zFYY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis CEO Brett P. 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