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Faces Sales Hole in Early 2030s After Trial Setback","url":"https://stock-news.laohu8.com/highlight/detail?id=2666158379","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2666158379?lang=en_us&edition=fundamental","pubTime":"2026-09-09 16:01","pubTimestamp":1788940860,"startTime":"0","endTime":"0","summary":"0801 GMT - Novartis's latest clinical-trial setback raises questions about the Swiss drugmaker's acquisition track record and leaves a sales hole to be plugged in the early 2030s, Deutsche Bank's Emmanuel Papadakis says in a research note. News that drug candidate del-desiran missed the target of a late-stage study in rare neuromuscular disorder known as myotonic dystrophy type 1 came shortly after cardiovascular drug pelacarsen failed another trial. Del-desiran was the first proof point for the recent $12 billion Avidity acquisition, the analyst says. Moreover, it leaves a hole to be addressed in the early 2030s when big drugs like Cosentyx, Kisqali and Kesimpta lose patent protection, he adds. Deutsche Bank cuts its recommendation on Novartis stock to hold from buy and trims its target price to 120 Swiss francs from 140 francs. 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Amgen's trial also uses a different primary endpoint that excludes stroke, and taken together, these factors may help turn a small numerical benefit into a statistically significant result, potentially around a 15% reduction in major cardiovascular events, the report said.UBS maintained its buy rating on Amgen stock and its $440 price target.Amgen 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Midday Stories: GE Aerospace to Acquire Consolidated Precision Products; Qualcomm Issues Share Warrant to Amazon","url":"https://stock-news.laohu8.com/highlight/detail?id=2665379746","media":"MT Newswires Live","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665379746?lang=en_us&edition=fundamental","pubTime":"2026-09-08 23:45","pubTimestamp":1788882329,"startTime":"0","endTime":"0","summary":"All three major US stock indexes fell in late-morning trading Tuesday as oil prices climbed and investors monitored developments in the US-Iran war and US trade negotiations with Canada.In company 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Failed Trial for Cholesterol Drug Leads to Broad Biopharma Selloff","url":"https://stock-news.laohu8.com/highlight/detail?id=2665937529","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665937529?lang=en_us&edition=fundamental","pubTime":"2026-09-08 21:53","pubTimestamp":1788875580,"startTime":"0","endTime":"0","summary":"Shares of Novartis, Amgen and Ionis tumbled on Tuesday morningNovartis' disclosure that a Lp(a)-lowering drug failed to reduce the risk of cardiovascular events like heart attacks and stroke in a 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Down over 12%, on Pace for Record Percent Decrease","url":"https://stock-news.laohu8.com/highlight/detail?id=2665375990","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665375990?lang=en_us&edition=fundamental","pubTime":"2026-09-08 21:39","pubTimestamp":1788874740,"startTime":"0","endTime":"0","summary":"Novartis AG Sponsored ADR  is currently at $140.06, down $19.93 or 12.46%--Would be lowest close since Jan. 5, 2026, when it closed at $137.91--Would be largest percent decrease on record --Currently down two consecutive days; down 14.12% over this period--Worst two day stretch on record --Down 7.89% month-to-date--Up 1.59% year-to-date--Down 16.94% from its all-time closing high of $168.62 on Feb. 27, 2026--Up 9.38% from 52 weeks ago , when it closed at $128.05--Down 16.94% from its 52-week closing high of $168.62 on Feb. 27, 2026--Up 14.99% from its 52-week closing low of $121.80 on Oct. 29, 2025--Traded as low as $139.45; lowest intraday level since Jan. 6, 2026, when it hit $139.09--Down 12.84% at today's intraday low; largest intraday percent decrease since March 16, 2020, when it fell as much as 13.1%All data as of 9:37:10 AM ETSource: Dow Jones Market Data, 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The sharp decline was triggered by a cascade of three clinical trial failures...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Novartis Plunges as Three Clinical Trial Failures in One Week Spark Selloff","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NVS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665373903","title":"Sector Update: Healthcare","url":"https://stock-news.laohu8.com/highlight/detail?id=2665373903","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665373903?lang=en_us&edition=fundamental","pubTime":"2026-09-08 21:02","pubTimestamp":1788872523,"startTime":"0","endTime":"0","summary":"Financial stocks were flat to lower pre-bell Tuesday, with the iShares Biotechnology ETF  inactive and the State Street Health Care Select Sector SPDR ETF  declining by 1.3%.Novartis  stock was down more than 12% after the company said its late-stage study evaluating delpacibart etedesiran in patients with myotonic dystrophy type 1 has failed to meet its primary endpoint of video hand opening time.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["XBI","IE0009355771.USD","LU0320765489.SGD","LABU","IE00BFTCPJ56.SGD","HCSG","PPH","BK4578","LU0029874061.USD","LU0211331839.USD","XLV","IBB","LU0208291251.USD","BK4137","MEDX","BK4007","LU0070302665.USD","BK4581","IE00B4R5TH58.HKD","NVS","IE00BJT1NW94.SGD","BK4532","BK4585","BK4588","LU0128526141.USD","IE00BJJMRZ35.SGD","IE00B2B36J28.USD","IE0002141913.USD"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":2,"totalSize":200,"code":"91000000","status":"200"}]}}