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Actuate Therapeutics Inc

1.04

+0.05635.72%

Volume:166.34K

Turnover:166.93K

Market Cap:24.88M

PE:-1.17

High:1.05

Open:1.00

Low:0.9400

Close:0.9837

52wk High:8.49

52wk Low:0.9000

Shares:23.93M

Float Shares:8.60M

Volume Ratio:1.48

T/O Rate:1.93%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.8859

EPS(LYR):-1.0574

ROE:-553.75%

ROA:-213.40%

PB:25.16

PE(LYR):-0.98

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Overview Company News Filings

Actuate to Present at the H.C. Wainwright 28th Annual Global Investment Conference

Actuate Reports Preclinical Synergy of Elraglusib with RAS Inhibitors in Pancreatic Cancer Models

Actuate Announces Promising Preclinical Data Showing Synergistic Activity of Elraglusib in Combination with Ras Inhibitors Zoldonrasib and Daraxonrasib

THOMSON REUTERS

Push for major rental change for millions of AussiesThe move would reduce affordability and security problems for renters across the country.3 min read

Actuate Therapeutics Price Target Maintained with a $15.00/Share by HC Wainwright & Co.

Analyst Reiterates Buy on Actuate with Unchanged $15 Price Target Ahead of Key Elraglusib Trials

Actuate Therapeutics Inc Reports Results for the Quarter Ended June 30 - Earnings Summary

Actuate Therapeutics Q2 FY26 Net Loss Narrows to $4.87 Million; Operating Loss Improves to $4.91 Million

Actuate Therapeutics Inc Expected to Post a Loss of 19 Cents a Share - Earnings Preview

Actuate Therapeutics Initiated at Buy by Rodman & Renshaw

Actuate Therapeutics’ Elraglusib Selected for Evaluation in Beacon2 Trial for High-Risk Pediatric Neuroblastoma

THOMSON REUTERS

Actuate says elraglusib enters BEACON2 Phase 1/2 trial in relapsed pediatric neuroblastoma

Actuate Therapeutics’ Elraglusib Selected for Evaluation in BEACON2 Trial for High-Risk Pediatric Neuroblastoma

Actuate Therapeutics posts ASCO presentation on elraglusib plus chemotherapy in metastatic pancreatic cancer

Actuate says Phase 2 data show elraglusib plus chemo lifts survival in first-line metastatic pancreatic cancer

Actuate Therapeutics Announces Asco Poster Presentations Demonstrating Compelling Clinical and Biomarker Data for Elraglusib in First-Line Metastatic Pancreatic Cancer

THOMSON REUTERS

Actuate Therapeutics Announces ASCO Poster Presentations Demonstrating Compelling Clinical and Biomarker Data for Elraglusib in First-Line Metastatic Pancreatic Cancer

Actuate Therapeutics Stockholders Elect Directors, Ratify Auditor

Actuate Therapeutics shareholders elected two directors at annual meeting

Actuate Therapeutics Price Target Maintained With a $15.00/Share by HC Wainwright & Co.

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04:11","pubTimestamp":1786738292,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics Q2 FY26 net loss narrows to $4.87 million; operating loss improves to $4.91 millionActuate Therapeutics posted a Q2 net loss of $4.87 million, narrowing from $5.95 million a year ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260814:nNDL19W7md:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2659900625","title":"Actuate Therapeutics Inc Expected to Post a Loss of 19 Cents a Share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2659900625","media":"Reuters","labels":["dataReport","preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2659900625?lang=en_us&edition=fundamental","pubTime":"2026-08-13 04:16","pubTimestamp":1786565765,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics Inc <ACTU.OQ> expected to post a loss of19cents a share - Earnings PreviewActuate Therapeutics IncACTU.OQACTU.Ois expected to  show no change in quarterly revenue when it reports ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260812:nL8N44923J:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2655772138","title":"Actuate Therapeutics Initiated at Buy by Rodman & Renshaw","url":"https://stock-news.laohu8.com/highlight/detail?id=2655772138","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2655772138?lang=en_us&edition=fundamental","pubTime":"2026-07-30 20:29","pubTimestamp":1785414540,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ACTU/analyst-ratings","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2642287462","title":"Actuate Therapeutics’ Elraglusib Selected for Evaluation in Beacon2 Trial for High-Risk Pediatric Neuroblastoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2642287462","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642287462?lang=en_us&edition=fundamental","pubTime":"2026-06-09 19:45","pubTimestamp":1781005533,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260609:nFWN42H0JM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2642462256","title":"Actuate says elraglusib enters BEACON2 Phase 1/2 trial in relapsed pediatric neuroblastoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2642462256","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642462256?lang=en_us&edition=fundamental","pubTime":"2026-06-09 19:45","pubTimestamp":1781005526,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics’ elraglusib was selected for evaluation in BEACON2, a European Phase 1/2 platform trial in relapsed or refractory pediatric neuroblastoma.The study will test elraglusib with dinutuximab beta and chemotherapy, starting with a dose-confirmation stage focused on safety and dose selection.No BEACON2 results have been presented; data will be generated in the trial as it progresses.Prior early-stage clinical findings were previously reported, including a complete response in a heavily pretreated neuroblastoma patient in a separate Phase 1/2 study.The move expands elraglusib’s pediatric development path, supported by an FDA Rare Pediatric Disease designation for neuroblastoma.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260609:nNDL2TySKq:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4112","SG9999014005.SGD","SG9999014013.SGD","BK4139","LU0314104364.USD","IE00BKPKM429.USD","NDAQ","ACTU","LU2095319765.USD","IE00BN0W2T93.GBP","LU2210149790.SGD","LU2210150020.SGD","IE00B3QW5Z07.USD","IE00B64PRP62.GBP","BK4585","IE00BN0W2V16.EUR","SG9999014021.USD","IE00BGHQF748.EUR","BK4588","IE00BN0W2W23.USD","SG9999014039.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2642462229","title":"Actuate Therapeutics’ Elraglusib Selected for Evaluation in BEACON2 Trial for High-Risk Pediatric Neuroblastoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2642462229","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642462229?lang=en_us&edition=fundamental","pubTime":"2026-06-09 19:45","pubTimestamp":1781005500,"startTime":"0","endTime":"0","summary":"- BEACON2 is a landmark European multi-arm, multi-stage Phase 1/2 platform trial conducted and sponsored by the Cancer Research UK Clinical Trials Unit (CRCTU), University of Birmingham- Elraglusib wi","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/06/09/3308735/0/en/Actuate-Therapeutics-Elraglusib-Selected-for-Evaluation-in-BEACON2-Trial-for-High-Risk-Pediatric-Neuroblastoma.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2211817866.USD","IE00BYQQ9H92.USD","PK","BK4588","LU1093756325.SGD","IE00BFXG0V08.USD","BK4139","BK4533","BK4567","LU2413666699.HKD","ACTU","LU2413666426.HKD","BK4218","BK4585","BK4548","BK4121","MTD","LU1093756168.USD","IE00B5TLWC47.USD","LU1721428933.USD","LU0347712357.USD","BK4181"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640463409","title":"Actuate Therapeutics posts ASCO presentation on elraglusib plus chemotherapy in metastatic pancreatic cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2640463409","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640463409?lang=en_us&edition=fundamental","pubTime":"2026-06-02 21:41","pubTimestamp":1780407713,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics published a post-hoc efficacy and biomarker analysis from its phase 2 1801 Part 3B study in first-line metastatic pancreatic cancer.Landmark analysis in patients completing at least one cycle showed median overall survival of 12.5 months with elraglusib plus chemotherapy vs 8.5 months with chemotherapy alone.Subgroup results showed longer survival signals in patients with baseline albumin ≥3 g/dL or CA19-9 <8,000 U/mL on the elraglusib regimen.Exploratory biomarker work linked KRAS, TP53, CDKN2A, or SMAD4 alterations to worse survival only in the elraglusib arm.Outcomes appeared stronger in Europe than North America, with early mortality of 5.3% vs 15.4% in the elraglusib arm.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260602:nNDL1zZLg0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640220955","title":"Actuate says Phase 2 data show elraglusib plus chemo lifts survival in first-line metastatic pancreatic cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2640220955","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640220955?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:05","pubTimestamp":1780311945,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics reported Phase 2 elraglusib data in first-line metastatic pancreatic cancer at the 2026 ASCO Annual Meeting.Post-hoc analyses indicated longer survival in selected biomarker-defined patients receiving elraglusib with standard chemotherapy versus chemotherapy alone.A separate Phase 2 study suggested added clinical benefit when elraglusib was combined with FOLFIRINOX, with responses appearing deeper and more durable.Safety appeared manageable across regimens, supporting further development and potential positioning of elraglusib as a combination backbone therapy.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nNDLbBm954:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","BK4112","IE00BN0W2T93.GBP","SG9999014039.USD","IE00BN0W2V16.EUR","LU2210150020.SGD","IE00BKPKM429.USD","ACTU","BK4588","SG9999014005.SGD","LU0314104364.USD","SG9999014013.SGD","IE00B64PRP62.GBP","NDAQ","IE00B3QW5Z07.USD","LU2095319765.USD","BK4139","LU2210149790.SGD","IE00BGHQF748.EUR","SG9999014021.USD","IE00BN0W2W23.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640955964","title":"Actuate Therapeutics Announces Asco Poster Presentations Demonstrating Compelling Clinical and Biomarker Data for Elraglusib in First-Line Metastatic Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2640955964","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640955964?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:00","pubTimestamp":1780311602,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nTUAW3TV7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640407955","title":"Actuate Therapeutics Announces ASCO Poster Presentations Demonstrating Compelling Clinical and Biomarker Data for Elraglusib in First-Line Metastatic Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2640407955","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640407955?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:00","pubTimestamp":1780311600,"startTime":"0","endTime":"0","summary":"- Patients with KRAS wild-type (WT) genomics achieved significant improvement in median overall survival (mOS) when treated with elraglusib plus gemcitabine/Abraxane (GnP) versus GnP alone - Patients ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/06/01/3304175/0/en/Actuate-Therapeutics-Announces-ASCO-Poster-Presentations-Demonstrating-Compelling-Clinical-and-Biomarker-Data-for-Elraglusib-in-First-Line-Metastatic-Pancreatic-Cancer.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637347120","title":"Actuate Therapeutics Stockholders Elect Directors, Ratify Auditor","url":"https://stock-news.laohu8.com/highlight/detail?id=2637347120","media":"TIPRANKS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637347120?lang=en_us&edition=fundamental","pubTime":"2026-05-23 06:24","pubTimestamp":1779488665,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics, Inc. ( ($ACTU) ) has issued an update. On May 21, 2026, Actuate Therapeutics, Inc. held its virtual Annual Meeting of Stockho...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/actuate-therapeutics-stockholders-elect-directors-ratify-auditor?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/actuate-therapeutics-stockholders-elect-directors-ratify-auditor?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637344784","title":"Actuate Therapeutics shareholders elected two directors at annual meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2637344784","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637344784?lang=en_us&edition=fundamental","pubTime":"2026-05-23 04:44","pubTimestamp":1779482668,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics held its annual stockholder meeting on May 21, 2026.Stockholders elected Aaron G.L. Fletcher, Ph.D. and Jason Keyes to the board.Crowe LLP’s appointment as independent registered public accounting firm for the fiscal year ending Dec. 31, 2026 was ratified.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Actuate Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 22, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260522:nNDL9cBQ3T:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636003336","title":"Actuate Therapeutics Price Target Maintained With a $15.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2636003336","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636003336?lang=en_us&edition=fundamental","pubTime":"2026-05-19 01:57","pubTimestamp":1779127020,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ACTU/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  May 18, 2026 13:57 ET (17:57 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":1,"totalSize":51,"code":"91000000","status":"200"}]}}